Ddx4^{em1(icre)Jobo}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddx4^{em1(icre)Jobo}
• Name: DEAD box helicase 4; endonuclease-mediated mutation 1, Josephine Bowles
• MGI ID: MGI:7464282
• Synonyms: Ddx4^Cre, Ddx4^iCreJoBo, Ddx4-P2A-iCre
• Gene: Ddx4 Location: Chr13:112734867-112789009 bp, - strand Genetic Position: Chr13, 63.87 cM
• Alliance: Ddx4^{em1(icre)Jobo} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Ddx4^{em1(icre)Jobo} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ddx4 (MGI:102670)

• Using CRISPR/CAS9, the P2A-iCre cassette was inserted into the 3' of the Ddx4 gene. (J:334521)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ddx4 (mouse) Summary of all recombinase alleles driven by Ddx4. Comparative matrix view of recombinase activities Alliance mouse Ddx4 gene page

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx4 Mutation: 59 strains or lines available

References

• Original: J:334521 Burnet G, et al., Generation and characterization of a Ddx4-iCre transgenic line for deletion in the germline beginning at genital ridge colonization. Genesis. 2023 Mar;61(1-2):e23511
• All: 1 reference(s)