Gimap7^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gimap7^em1(IMPC)Tcp
• Name: GTPase, IMAP family member 7; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:7464999
• Gene: Gimap7 Location: Chr6:48695555-48701570 bp, + strand Genetic Position: Chr6, 23.69 cM
• Alliance: Gimap7^em1(IMPC)Tcp page
• IMPC: Gimap7 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ACCCCTACTCCGTCCGCTCA and CTGTGGTCCATCCGGTCAAG within exon ENSMUSE00000255842. This resulted in a 940-bp deletion of Chr15 from 33687003 to 33687942 (GRCm39) introducing a frameshift and premature stop codon. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gimap7 Mutation: 14 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)