Tg(MMTV-flpo)9Gcr
Transgene Detail

Summary

• Symbol: Tg(MMTV-flpo)9Gcr
• Name: transgene insertion 9, Gerhard Christofori
• MGI ID: MGI:7466135
• Synonyms: Tg(MMTV-Flpo)9Gcr)
• Transgene: Tg(MMTV-flpo)9Gcr Location: unknown
• Alliance: Tg(MMTV-flpo)9Gcr page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(MMTV-flpo)9Gcr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  virus	MMTV

• Mutation details: The codon-optimized Flp (Flpo) gene was placed under the control of the MMTV LTR promoter. Two funder lines (9 and 11) with high flpo activity were identified. One line (line 9) with more restricted flpo activity was established and used for the studies. (J:335073)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	MMTV (virus) Summary of all recombinase alleles driven by MMTV.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:335073 Luond F, et al., A Transgenic MMTV-Flippase Mouse Line for Molecular Engineering in Mammary Gland and Breast Cancer Mouse Models. J Mammary Gland Biol Neoplasia. 2019 Mar;24(1):39-45
• All: 3 reference(s)