Hhip^{tm1(cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Hhip^{tm1(cre/ERT2)Wtsi}
• Name: Hedgehog-interacting protein; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:7466293
• Synonyms: Hhip-CreERT2, Hhip-EGFP_T2A_CreERT2
• Gene: Hhip Location: Chr8:80692480-80784635 bp, - strand Genetic Position: Chr8, 37.95 cM, cytoband C3
• Alliance: Hhip^{tm1(cre/ERT2)Wtsi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:316922
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Hhip^{tm1(cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hhip (MGI:1341847)

• A EGFP_T2A_CreERT2 was inserted into the Hhip gene. (J:316922)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hhip (mouse) Summary of all recombinase alleles driven by Hhip. Comparative matrix view of recombinase activities Alliance mouse Hhip gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hhip Mutation: 44 strains or lines available

References

• Original: J:316922 Holmes G, et al., Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132
• All: 1 reference(s)