Prss29^{em1(cre/EGFP)Tesp}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss29^{em1(cre/EGFP)Tesp}
• Name: serine protease 29; endonuclease-mediated mutation 1, Thomas E Spencer
• MGI ID: MGI:7467066
• Synonyms: Prss29-Cre
• Gene: Prss29 Location: Chr17:25537628-25541658 bp, + strand Genetic Position: Chr17, 12.53 cM, cytoband A3.3
• Alliance: Prss29^{em1(cre/EGFP)Tesp} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:335131
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (No functional change, Recombinase, Reporter)
• Mutation: Insertion
• Prss29^{em1(cre/EGFP)Tesp} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prss29 (MGI:2149952)

• Mutation details: Using CRISPR technology, IRES-CreEGFP-pA elements followed by a neo-selection cassette were inserted after the STOP codon in exon 6 of the Prss29 gene in the Embryonic Stem (ES) cells. Successfully targeted ES cells were used to generate chimeric mice by blastocyst injection for germline transmission. (J:335131)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prss29 (mouse) Summary of all recombinase alleles driven by Prss29. Comparative matrix view of recombinase activities Alliance mouse Prss29 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss29 Mutation: 16 strains or lines available

Notes

Lentiviral gene trap injected into zygotes.

References

• Original: J:335131 Kelleher AM, et al., Prss29 Cre recombinase mice are useful to study adult uterine gland function. Genesis. 2022 Dec;60(10-12):e23493
• All: 1 reference(s)