Gh^em1(cre)Jmz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gh^em1(cre)Jmz
• Name: growth hormone; endonuclease-mediated mutation 1, Jeffrey M Zigman
• MGI ID: MGI:7467198
• Synonyms: GH-IRES-Cre
• Gene: Gh Location: Chr11:106191097-106192691 bp, - strand Genetic Position: Chr11, 68.89 cM, cytoband D
• Alliance: Gh^em1(cre)Jmz page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Gh^em1(cre)Jmz expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gh (MGI:95707)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gh (mouse) Summary of all recombinase alleles driven by Gh. Comparative matrix view of recombinase activities Alliance mouse Gh gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gh Mutation: 16 strains or lines available

References

• Original: J:318685 Gupta D, et al., Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions. Mol Metab. 2021 Nov;53:101258
• All: 1 reference(s)