Ubc^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ubc^{em1(cre/ERT2)Smoc}
• Name: ubiquitin C; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7467409
• Synonyms: Ubc^ERT2Cre
• Gene: Ubc Location: Chr5:125463029-125467081 bp, - strand Genetic Position: Chr5, 64.18 cM
• Alliance: Ubc^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Not Specified
• Ubc^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ubc (MGI:98889)

• An inducible cre fusion gene was knocked into the gene. (J:318741)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ubc (mouse) Summary of all recombinase alleles driven by Ubc. Alliance mouse Ubc gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubc Mutation: 5 strains or lines available

References

• Original: J:318741 Li R, et al., Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation. Theranostics. 2022;12(2):976-998
• All: 3 reference(s)