Flrt3^{tm4(cre/ERT2)Kln}
Targeted Allele Detail

Summary

• Symbol: Flrt3^{tm4(cre/ERT2)Kln}
• Name: fibronectin leucine rich transmembrane protein 3; targeted mutation 3, Rudiger Klein
• MGI ID: MGI:7467420
• Synonyms: Flrt3^Cre/ERT2
• Gene: Flrt3 Location: Chr2:140500118-140513396 bp, - strand Genetic Position: Chr2, 69.2 cM
• Alliance: Flrt3^{tm4(cre/ERT2)Kln} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319358
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Flrt3^{tm4(cre/ERT2)Kln} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Flrt3 (MGI:1918686)

• Mutation details: The targeting construct inserted the CreERT2 sequence, an SV40 polyadenylation signal, and a loxP-flanked neo cassette into exon 3 of the Flrt3 gene via homologous recombination in ES cells. (J:319358)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Flrt3 (mouse) Summary of all recombinase alleles driven by Flrt3. Comparative matrix view of recombinase activities Alliance mouse Flrt3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Flrt3 Mutation: 44 strains or lines available

References

• Original: J:319358 Ruff T, et al., FLRT3 Marks Direction-Selective Retinal Ganglion Cells That Project to the Medial Terminal Nucleus. Front Mol Neurosci. 2021;14:790466
• All: 1 reference(s)