Mafa^em1(cre)Xzd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mafa^em1(cre)Xzd
• Name: MAF bZIP transcription factor A; endonuclease-mediated mutation 1, Xinzhong Dong
• MGI ID: MGI:7468617
• Synonyms: MafA-Cre
• Gene: Mafa Location: Chr15:75617339-75620077 bp, - strand Genetic Position: Chr15, 34.82 cM
• Alliance: Mafa^em1(cre)Xzd page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Recombinase)
• Mutation: Insertion
• Mafa^em1(cre)Xzd expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mafa (MGI:2673307)

• Using a CRISPR-Cas9 approach, the entire Mafa coding sequence was replaced with Cre transgene. (J:319932)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mafa (mouse) Summary of all recombinase alleles driven by Mafa. Comparative matrix view of recombinase activities Alliance mouse Mafa gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mafa Mutation: 20 strains or lines available

References

• Original: J:319932 Xu Q, et al., Astrocytes contribute to pain gating in the spinal cord. Sci Adv. 2021 Nov 5;7(45):eabi6287
• All: 1 reference(s)