Axin2tm2.1Niba
Targeted Allele Detail
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Symbol: |
Axin2tm2.1Niba |
Name: |
axin 2; targeted mutation 2.1, Nick Barker |
MGI ID: |
MGI:7468752 |
Synonyms: |
Axin2-2A-EGFP |
Gene: |
Axin2 Location: Chr11:108811175-108841609 bp, + strand Genetic Position: Chr11, 71.83 cM
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Alliance: |
Axin2tm2.1Niba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:319855
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Reporter) |
Mutation: |
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Insertion
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Mutation details: Sequence for the 2A self-cleaving peptide, the EGFP fluorescent marker gene and a loxP site flanked neomycin resistance gene cassette were inserted immediately before the stop codon. The neo cassette was removed through subsequent cre-mediated recombination. This allele expresses the endogenous peptide and the inserted EGFP peptide.
(J:319855)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Axin2 Mutation: |
42 strains or lines available
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Original: |
J:319855 Tan SH, et al., A constant pool of Lgr5(+) intestinal stem cells is required for intestinal homeostasis. Cell Rep. 2021 Jan 26;34(4):108633 |
All: |
1 reference(s) |
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