Tg(Vsx1-cre/ERT2)471Fclo
Transgene Detail

Summary

• Symbol: Tg(Vsx1-cre/ERT2)471Fclo
• Name: transgene insertion 471, Frederic Clotman
• MGI ID: MGI:7482341
• Synonyms: Vsx1-CreER^T2BAC
• Transgene: Tg(Vsx1-cre/ERT2)471Fclo Location: unknown
• Alliance: Tg(Vsx1-cre/ERT2)471Fclo page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Vsx1-cre/ERT2)471Fclo expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vsx1 (MGI:1890816)

• Mutation details: The transgene consists of a BAC (RP23-341J5) with 160 kb around the Vsx1 locus modified by homologous recombination in E. coli to insert the CreERT2 coding sequence at the Vsx1 translation initiation codon. Nine founder lines were obtained, and line 471 with high recombination was established and used for the studies. (J:322776)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vsx1 (mouse) Summary of all recombinase alleles driven by Vsx1. Comparative matrix view of recombinase activities Alliance mouse Vsx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:322776 Baudouin C, et al., Generation and characterization of a tamoxifen-inducible Vsx1-CreER(T2) line to target V2 interneurons in the mouse developing spinal cord. Genesis. 2021 Aug;59(7-8):e23435
• All: 2 reference(s)