Kcnip2^{tm1(cre/ERT2)Yifz}
Targeted Allele Detail

Summary

• Symbol: Kcnip2^{tm1(cre/ERT2)Yifz}
• Name: Kv channel-interacting protein 2; targeted mutation 1, Yifeng Zhang
• MGI ID: MGI:7482482
• Synonyms: Kcnip2-CreER
• Gene: Kcnip2 Location: Chr19:45780785-45804948 bp, - strand Genetic Position: Chr19, 38.75 cM, cytoband D1
• Alliance: Kcnip2^{tm1(cre/ERT2)Yifz} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322812
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Kcnip2^{tm1(cre/ERT2)Yifz} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Kcnip2 (MGI:2135916)

• Mutation details: The allele was generated by inserting the 2a-CreERT2-2a-mCherry fragment into exon 10 of the Kcnip2 gene, replacing the stop codon via homologous recombination. The mCherry protein is not expressed in the retina at a detectable level. (J:322812)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kcnip2 (mouse) Summary of all recombinase alleles driven by Kcnip2. Comparative matrix view of recombinase activities Alliance mouse Kcnip2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnip2 Mutation: 28 strains or lines available

References

• Original: J:322812 Wang F, et al., OFF-transient alpha RGCs mediate looming triggered innate defensive response. Curr Biol. 2021 Jun 7;31(11):2263-2273.e3
• All: 2 reference(s)