Fto^{Gt(cre/ERT2)1Card}
Gene trapped Allele Detail

Summary

• Symbol: Fto^{Gt(cre/ERT2)1Card}
• Name: FTO alpha-ketoglutarate dependent dioxygenase; gene trap Ayu21-T95, Center for Animal Resources and Development
• MGI ID: MGI:7482569
• Synonyms: Fto^{Gt(Ayu21-T95*mERT2)1Card}
• Gene: Fto Location: Chr8:92040153-92395067 bp, + strand Genetic Position: Chr8, 44.34 cM
• Alliance: Fto^{Gt(cre/ERT2)1Card} page

Mutation origin

• Mutant Cell Line: Ayu21-T95
• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: KTPU8 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Gene trapped (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion Vector: pU-21T
• Fto^{Gt(cre/ERT2)1Card} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fto (MGI:1347093)

• Mutation details: RMCE on Fto^{Gt(Ayu21-T95)Imeg} inserted the inducible fusion product of cre recombinase and modified estrogen receptor (ERT2). (J:104881)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fto (mouse) Summary of all recombinase alleles driven by Fto. Alliance mouse Fto gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fto Mutation: 75 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)