Pla1a^em1Appsc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pla1a^em1Appsc
• Name: phospholipase A1 member A; endonuclease-mediated mutation 1, Applied StemCell
• MGI ID: MGI:7482743
• Gene: Pla1a Location: Chr16:38216479-38253507 bp, - strand Genetic Position: Chr16, 26.83 cM
• Alliance: Pla1a^em1Appsc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 297-bp deletion of exon 2. (J:333902)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla1a Mutation: 33 strains or lines available

References

• Original: J:333902 Zhao Y, et al., Phospholipase A1 Member A Deficiency Alleviates Mannan-Induced Psoriatic Arthritis in Mice Model. Int J Mol Sci. 2022 Aug 2;23(15)
• All: 1 reference(s)