Dpt^{tm1.1(cre/ERT2)Snjt}
Targeted Allele Detail

Summary

• Symbol: Dpt^{tm1.1(cre/ERT2)Snjt}
• Name: dermatopontin; targeted mutation 1.1, Shannon J Turley
• MGI ID: MGI:7484702
• Synonyms: Dpt^IresCreERT2
• Gene: Dpt Location: Chr1:164624232-164651843 bp, + strand Genetic Position: Chr1, 72.12 cM, cytoband H2
• Alliance: Dpt^{tm1.1(cre/ERT2)Snjt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325754
• Parent Cell Line: C2 (Nagy) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Dpt^{tm1.1(cre/ERT2)Snjt} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dpt (MGI:1928392)

• Mutation details: The targeting construct inserted an IRES-CREERT2-SV40-FRT-pgk-neo-FRT immediately after the STOP codon (TAG) of exon 4 of the Dpt gene. Flp-mediated recombination removed the selection cassette. (J:325754)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dpt (mouse) Summary of all recombinase alleles driven by Dpt. Comparative matrix view of recombinase activities Alliance mouse Dpt gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpt Mutation: 16 strains or lines available

References

• Original: J:325754 Buechler MB, et al., Cross-tissue organization of the fibroblast lineage. Nature. 2021 May;593(7860):575-579
• All: 2 reference(s)