Dkk1^{tm1(cre/ERT2)Pmy}
Targeted Allele Detail

Summary

• Symbol: Dkk1^{tm1(cre/ERT2)Pmy}
• Name: dickkopf WNT signaling pathway inhibitor 1; targeted mutation 1, Peggy Myung
• MGI ID: MGI:7485774
• Synonyms: Dkk1CreER
• Gene: Dkk1 Location: Chr19:30523276-30526896 bp, - strand Genetic Position: Chr19, 25.16 cM, cytoband C2
• Alliance: Dkk1^{tm1(cre/ERT2)Pmy} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324528
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Not Specified
• Dkk1^{tm1(cre/ERT2)Pmy} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dkk1 (MGI:1329040)

• Dkk1 with CreER knock-in allele. No molecular details are provided. (J:324528)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dkk1 (mouse) Summary of all recombinase alleles driven by Dkk1. Comparative matrix view of recombinase activities Alliance mouse Dkk1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dkk1 Mutation: 18 strains or lines available

References

• Original: J:324528 Qu R, et al., Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022 Apr 25;57(8):1053-1067.e5
• All: 1 reference(s)