Mtmr9^tm1Wum
Targeted Allele Detail

Summary

• Symbol: Mtmr9^tm1Wum
• Name: myotubularin related protein 9; targeted mutation 1, Washington University School of Medicine
• MGI ID: MGI:7488201
• Gene: Mtmr9 Location: Chr14:63757100-63781402 bp, - strand Genetic Position: Chr14, 33.32 cM
• Alliance: Mtmr9^tm1Wum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:336167
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Dominant negative, Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A Velocigene construct from the KOMP project was obtained and used to create this null allele that deletes the entire coding sequence and replaces it with a lacZ and neomycin resistance cassette (J:336167)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtmr9 Mutation: 22 strains or lines available

References

• Original: J:336167 Zou J, et al., The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. Adv Biol Regul. 2012;52(1):282-9
• All: 1 reference(s)