Pou2af2^em1Crva
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pou2af2^em1Crva
• Name: POU domain, class 2, associating factor 2; endonuclease-mediated mutation 1, Christopher R Vakoc
• MGI ID: MGI:7490316
• Synonyms: C11orf53^-
• Gene: Pou2af2 Location: Chr9:51200986-51240224 bp, - strand Genetic Position: Chr9, 28.05 cM, cytoband B
• Alliance: Pou2af2^em1Crva page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 4-bp deletion (GGAT) of the start codon. (J:325394)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou2af2 Mutation: 12 strains or lines available

References

• Original: J:325394 Wu XS, et al., OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 2022 May 16
• All: 1 reference(s)