Tg(Rr436-GCaMP6*,-mKeima*)3AHmd
Transgene Detail
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Symbol: |
Tg(Rr436-GCaMP6*,-mKeima*)3AHmd |
Name: |
transgene insertion 3A, Hiroshi Hamada |
MGI ID: |
MGI:7492208 |
Synonyms: |
Tg(Nodal NDE-5HT6/GCaMP6, 5HT6/mKeima)3AHmd |
Transgene: |
Tg(Rr436-GCaMP6*,-mKeima*)3AHmd Location: unknown
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Alliance: |
Tg(Rr436-GCaMP6*,-mKeima*)3AHmd page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Tg(Rr436-GCaMP6*,-mKeima*)3AHmd expression driven by
2 genes
Transgene expression driven by:
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Mutation details: The transgene contains the a crown cell-specific enhancer derived from the mouse Nodal gene driving expression of cilia-targeted GCaMP6 and mKeima reporter genes (5-hydroxytryptamine receptor isoform 6; 5HT6/GCaMP6, 5HT6/mKeima). GCaMP6 contains a RSET tag, chicken smooth muscle M13, Jellyfish circularly permutated EGFP (cpEGFP) cDNA, and rat calmodulin (CaM) cDNA (aa.2-148). Line 3A was generated.
(J:336740)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:336740 Katoh TA, et al., Immotile cilia mechanically sense the direction of fluid flow for left-right determination. Science. 2023 Jan 6;379(6627):66-71 |
All: |
1 reference(s) |
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