Ct55^em2Xdzg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ct55^em2Xdzg
• Name: cancer/testis antigen 55; endonuclease-mediated mutation 2, Xiao-Dong Zhang
• MGI ID: MGI:7494107
• Synonyms: Ct55 KO
• Gene: Ct55 Location: ChrX:52726622-52740532 bp, + strand Genetic Position: ChrX, 29.99 cM
• Alliance: Ct55^em2Xdzg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of exons 2-4. (J:337211)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ct55 Mutation: 8 strains or lines available

References

• Original: J:337211 Zhang G, et al., Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice. Cell Death Differ. 2023 Feb;30(2):500-514
• All: 1 reference(s)