Rorb^hstp-4J
Spontaneous Allele Detail

Summary

• Symbol: Rorb^hstp-4J
• Name: RAR-related orphan receptor beta; high stepper 4 Jackson
• MGI ID: MGI:7496018
• Synonyms: h2
• Gene: Rorb Location: Chr19:18907969-19088560 bp, - strand Genetic Position: Chr19, 13.28 cM
• Alliance: Rorb^hstp-4J page

Mutation origin

• Strain of Origin: B6(Cg)-Tyr^c-2J/J

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Undefined
• Mutation details: This spontaneous mutation was defined as an allele of this gene by failed complementation testing. Expression of the Rorb1 transcript in brain is significantly reduced and the Rorb2 transcript significantly increased in retina. (J:337403)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rorb Mutation: 41 strains or lines available

References

• Original: J:337403 Murray GC, et al., An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response. G3 (Bethesda). 2023 Jun 10
• All: 1 reference(s)