Traf7^tm1.1Ifd
Targeted Allele Detail

Summary

• Symbol: Traf7^tm1.1Ifd
• Name: TNF receptor-associated factor 7; targeted mutation 1.1, Ian Dunn
• MGI ID: MGI:7506866
• Gene: Traf7 Location: Chr17:24727824-24746912 bp, - strand Genetic Position: Chr17, 12.4 cM
• Alliance: Traf7^tm1.1Ifd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339061
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP-F3-hygromycin-F3 selection cassette was placed in intron 1 and an FRT-ivNeo-FRT-loxP cassette was positioned 257bp downstream of exon 14. Flp-mediated recombination removed the hygromycin and neomycin cassettes. (J:101977, J:339061)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Traf7 Mutation: 45 strains or lines available

Notes

IN2 ES cells = C57BL/6N

References

• Original: J:339061 Tsitsikov EN, et al., TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development. iScience. 2023 Aug 18;26(8):107474
• All: 3 reference(s)