Tmem232^em1Shliu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem232^em1Shliu
• Name: transmembrane protein 232; endonuclease-mediated mutation 1, Shangming Liu
• MGI ID: MGI:7511695
• Gene: Tmem232 Location: Chr17:65562994-65847777 bp, - strand Genetic Position: Chr17, 34.9 cM
• Alliance: Tmem232^em1Shliu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 21,844-bp deletion encompassing exons 4 to 8. (J:338029)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem232 Mutation: 41 strains or lines available

References

• Original: J:338029 He X, et al., Deficiency of the Tmem232 Gene Causes Male Infertility with Morphological Abnormalities of the Sperm Flagellum in Mice. Cells. 2023 Jun 13;12(12)
• All: 1 reference(s)