Amhr2^{em1(cre/ERT2)Bult}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Amhr2^{em1(cre/ERT2)Bult}
• Name: anti-Mullerian hormone type 2 receptor; endonuclease-mediated mutation 1, Carol Bult
• MGI ID: MGI:7511885
• Synonyms: Amhr2-CRE-ERT2
• Gene: Amhr2 Location: Chr15:102353802-102363068 bp, + strand Genetic Position: Chr15, 57.58 cM
• Alliance: Amhr2^{em1(cre/ERT2)Bult} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Amhr2^{em1(cre/ERT2)Bult} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Amhr2 (MGI:105062)

• CRISPR/Cas9 mediated knockin by a 2A-cre/ERT2 replacing the stop codon in the Amhr2 gene. (J:338349)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Amhr2 (mouse) Summary of all recombinase alleles driven by Amhr2. Comparative matrix view of recombinase activities Alliance mouse Amhr2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Amhr2 Mutation: 29 strains or lines available

References

• Original: J:338349 Chauvin M, et al., Cancer-associated mesothelial cells are regulated by the anti-Mullerian hormone axis. Cell Rep. 2023 Jul 13;42(7):112730
• All: 1 reference(s)