Mir202^em1Hncs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir202^em1Hncs
• Name: microRNA 202; endonuclease-mediated mutation 1, Chunsheng Han
• MGI ID: MGI:7511896
• Synonyms: miR-202 KO
• Gene: Mir202 Location: Chr7:139537602-139537673 bp, - strand Genetic Position: Chr7, 84.93 cM
• Alliance: Mir202^em1Hncs page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a deletion of a 155-bp fragment containing the whole transcribed region of miR-202. (J:338367)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir202 Mutation: 0 strains or lines available

References

• Original: J:338367 Chen J, et al., MicroRNA-202 safeguards meiotic progression by preventing premature SEPARASE-mediated REC8 cleavage. EMBO Rep. 2022 Aug 3;23(8):e54298
• All: 2 reference(s)