Tmem119^em1(cre)Mari
Chemically induced Allele Detail

Summary

• Symbol: Tmem119^em1(cre)Mari
• Name: transmembrane protein 119; endonuclease-mediated mutation 1, Thomas Marichal
• MGI ID: MGI:7513910
• Synonyms: Tmem119^Cre
• Gene: Tmem119 Location: Chr5:113931790-113938457 bp, - strand Genetic Position: Chr5, 55.55 cM
• Alliance: Tmem119^em1(cre)Mari page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (other) (Recombinase)
• Mutation: Insertion
• Tmem119^em1(cre)Mari expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tmem119 (MGI:2385228)

• Mutation details: Using CRISPR/Cas9-mediated genome engineering, a Cre-polyA cassette was introduced in the Tmem119 gene upstream of the ATG start codon. (J:338559)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tmem119 (mouse) Summary of all recombinase alleles driven by Tmem119. Alliance mouse Tmem119 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem119 Mutation: 26 strains or lines available

References

• Original: J:338559 Vanneste D, et al., MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nat Immunol. 2023 May;24(5):827-840
• All: 1 reference(s)