Gpatch2^em1Boui
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpatch2^em1Boui
• Name: G patch domain containing 2; endonuclease-mediated mutation 1, Philippe Bouillet
• MGI ID: MGI:7514926
• Gene: Gpatch2 Location: Chr1:186947705-187083901 bp, + strand Genetic Position: Chr1, 90.59 cM, cytoband H5
• Alliance: Gpatch2^em1Boui page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9-mediated recombination using 2 guide RNAs created a deletion of exon 3. Immunoblot analysis confirmed the loss of expression in testes from homozygous mice. (J:336774)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpatch2 Mutation: 21 strains or lines available

References

• Original: J:336774 Dalseno D, et al., Deletion of Gpatch2 does not alter Tnf expression in mice. Cell Death Dis. 2023 Mar 27;14(3):214
• All: 1 reference(s)