Card19^tm1Rwen
Targeted Allele Detail

Summary

• Symbol: Card19^tm1Rwen
• Name: caspase recruitment domain family, member 19; targeted mutation 1, Renren Wen
• MGI ID: MGI:7514948
• Gene: Card19 Location: Chr13:49356426-49369471 bp, - strand Genetic Position: Chr13, 25.15 cM
• Alliance: Card19^tm1Rwen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:336763
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo gene replaced a genomic region including exons 2 - 6. (J:336763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card19 Mutation: 13 strains or lines available

References

• Original: J:336763 Zheng Y, et al., CARD19, a Novel Regulator of the TAK1/NF-kappaB Pathway in Self-Reactive B Cells. J Immunol. 2023 May 1;210(9):1222-1235
• All: 1 reference(s)