Tg(TCF/Lef1-cre/ERT2)#Ypc
Transgene Detail

Summary

• Symbol: Tg(TCF/Lef1-cre/ERT2)#Ypc
• Name: transgene insertion, YiPing Chen
• MGI ID: MGI:7515000
• Synonyms: Tcf/Lef^CreERT2
• Transgene: Tg(TCF/Lef1-cre/ERT2)#Ypc Location: unknown
• Alliance: Tg(TCF/Lef1-cre/ERT2)#Ypc page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Mutation: Insertion
• Tg(TCF/Lef1-cre/ERT2)#Ypc expression driven by 2 genes
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hspa1b (MGI:99517)
  mouse	Hspa1b (MGI:99517)

• Mutation details: The transgene was designed with six copies of a T cell-specific transcription factor/lymphoid enhancer-binding factor 1 (TCF/Lef1) DNA binding site and a heat shock protein 1B (Hspa1b) minimal promoter driving expression of a cre/ERT2 fusion protein followed by a simian virus 40 (SV40) polyadenylation signal. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:338731)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hspa1b (mouse) Summary of all recombinase alleles driven by Hspa1b. Comparative matrix view of recombinase activities Alliance mouse Hspa1b gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:338731 Liu Z, et al., Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/beta-catenin signaling in mammals. Elife. 2022 May 3;11:e77740
• All: 1 reference(s)