Amn^{em1(cre/ERT2)Fuzh}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Amn^{em1(cre/ERT2)Fuzh}
• Name: amnionless; endonuclease-mediated mutation 1, Fujian Zhang
• MGI ID: MGI:7516282
• Synonyms: AMN-CreERT2-mEGFP
• Gene: Amn Location: Chr12:111237530-111242860 bp, + strand Genetic Position: Chr12, 60.94 cM
• Alliance: Amn^{em1(cre/ERT2)Fuzh} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Mutation: Insertion
• Amn^{em1(cre/ERT2)Fuzh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Amn (MGI:1934943)

• Mutation details: Using the CRISPR/Cas9 technology, a P2A-CreERT2-P2A-mEGFP cassette was inserted before the stop codon of the mouse Amn gene. gene (J:338444)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Amn (mouse) Summary of all recombinase alleles driven by Amn. Comparative matrix view of recombinase activities Alliance mouse Amn gene page

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amn Mutation: 19 strains or lines available

References

• Original: J:338444 Liang S, et al., Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse. Front Cell Dev Biol. 2023;11:1171637
• All: 1 reference(s)