Gt(ROSA)26Sor^{tm13(dreo)Maoh}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm13(dreo)Maoh}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 13, Masato Ohtsuka
• MGI ID: MGI:7516500
• Synonyms: Rosa-Dre
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm13(dreo)Maoh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:336136
• Parent Cell Line: EGR-101 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm13(dreo)Maoh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gt(ROSA)26Sor (MGI:104735)

• Mutation details: The targeting construct inserted Dre (derived from custom codon-optimized Dre)-pA into the Gt(ROSA)26Sor locus driven under its endogenous promoter. (J:336136, J:303408)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gt(ROSA)26Sor (mouse) Summary of all recombinase alleles driven by Gt(ROSA)26Sor. Comparative matrix view of recombinase activities Alliance mouse Gt(ROSA)26Sor gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:336136 Ohtsuka M, et al., One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT). BMC Genomics. 2015 Apr 9;16:274
• All: 2 reference(s)