Mageb4^em2Zhpw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mageb4^em2Zhpw
• Name: MAGE family member B4; endonuclease-mediated mutation 2, Zhengpin Wang
• MGI ID: MGI:7516757
• Synonyms: Mageb4^KO2
• Gene: Mageb4 Location: ChrX:85293862-85299825 bp, - strand Genetic Position: ChrX, 39.71 cM
• Alliance: Mageb4^em2Zhpw page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intragenic deletion, Single point mutation
• CRISPR-targeting of exon 3 inserted a transversion (G to T) mutation and deleted 88bp. (J:338693)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mageb4 Mutation: 1 strain or line available

References

• Original: J:338693 Li N, et al., MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice. Biochem Biophys Res Commun. 2023 Jul 10;675:46-53
• All: 1 reference(s)