Cacna1a^em1Andm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cacna1a^em1Andm
• Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; endonuclease-mediated mutation 1, Michael G Anderson
• MGI ID: MGI:7518212
• Gene: Cacna1a Location: Chr8:85065268-85366875 bp, + strand Genetic Position: Chr8, 40.95 cM
• Alliance: Cacna1a^em1Andm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9-mediated mutation in Cacna1a on a pure C57BL/6J background. The mutation is a 1-bp coding sequence insertion in the targeted exon. Predicted to cause frameshift and premature STOP in the targeted exon. (J:338850)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacna1a Mutation: 118 strains or lines available

References

• Original: J:338850 Meyer KJ, et al., Direct Data Submission of Multiple Allele. MGI Direct Data Submission. 2023
• All: 1 reference(s)