Tg(Aicda-cre,-CD2)dME1Hon
Transgene Detail

Summary

• Symbol: Tg(Aicda-cre,-CD2)dME1Hon
• Name: transgene insertion dME1, Tasuku Honjo
• MGI ID: MGI:7519082
• Synonyms: dME-ac-cre, Tg(Aicda*dME-cre,-CD2)1Hon
• Transgene: Tg(Aicda-cre,-CD2)dME1Hon Location: unknown
• Alliance: Tg(Aicda-cre,-CD2)dME1Hon page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Aicda-cre,-CD2)dME1Hon expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aicda (MGI:1342279)

• Mutation details: The transgene contains the mouse Aicda genomic DNA with c-Myb- and E2F-binding sites (the silencing elements) that were deleted in the regulatory region 2, human CD2 cDNA reporter, Phage P1 Cre, SV40 polyA signal, yeast FRT site, and EMCV internal ribosomal entry site (ires). Two lines were generated with similar expression patterns. Line 1 is representative of all the lines. (J:338966)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (mouse) Summary of all recombinase alleles driven by Aicda. Comparative matrix view of recombinase activities Alliance mouse Aicda gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:338966 Huong le T, et al., In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression. PLoS One. 2013;8(4):e61433
• All: 1 reference(s)