Tg(CD2-Lrrc32,-EGFP)1Hfuj
Transgene Detail

Summary

• Symbol: Tg(CD2-Lrrc32,-EGFP)1Hfuj
• Name: transgene insertion 1, Hodaka Fujii
• MGI ID: MGI:7519098
• Synonyms: Tg(CD2-Lrrc32,GFP)1Hfuj
• Transgene: Tg(CD2-Lrrc32,-EGFP)1Hfuj Location: unknown
• Alliance: Tg(CD2-Lrrc32,-EGFP)1Hfuj page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CD2-Lrrc32,-EGFP)1Hfuj expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lrrc32 (MGI:93882)

• Tg(CD2-Lrrc32,-EGFP)1Hfuj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CD2 (914)

  Cd2	(MGI:88320)

• Mutation details: The transgene contains the human CD2 promoter, moues GARP (LRRC32) cDNA, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (IRES), Aequorea victoria enhanced green fluorescent protein (GFP), human CD2 polyA signal, and human CD2 locus control region. (J:202565)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:202565 Zhou AX, et al., GARP-TGF-beta complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo. J Immunol. 2013 May 15;190(10):5057-64
• All: 1 reference(s)