Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho
Transgene Detail

Summary

• Symbol: Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho
• Name: transgene insertion, Hyun-Jai Cho
• MGI ID: MGI:7520361
• Synonyms: LPAR4_CreERT2_IRES_EGFP_TG
• Transgene: Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho Location: unknown
• Alliance: Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  LPAR4 (2846)

  Lpar4

  (MGI:1925384)

• Mutation details: A 6.6 kb fragment containing the human LPAR4 promoter drives the cre/ERT2 sequence separated by IRES and EGFP-pA. The resulting construct was linearized and injected into single-cell embryos. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:338876)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	LPAR4 (human) Summary of all recombinase alleles driven by LPAR4. Comparative matrix view of recombinase activities Alliance human LPAR4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:338876 Lee JW, et al., SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction. Exp Mol Med. 2023 Jul;55(7):1424-1436
• All: 1 reference(s)