Pnp2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pnp2^em1Smoc
• Name: purine-nucleoside phosphorylase 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7520368
• Gene: Pnp2 Location: Chr14:51193598-51202206 bp, + strand Genetic Position: Chr14, 26.32 cM
• Alliance: Pnp2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 2. (J:339075)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pnp2 Mutation: 30 strains or lines available

References

• Original: J:339075 Fan KQ, et al., Stress-Induced Metabolic Disorder in Peripheral CD4(+) T Cells Leads to Anxiety-like Behavior. Cell. 2019 Oct 31;179(4):864-879.e19
• All: 1 reference(s)