Tg(Tff2-EGFP,-cre)3aTcw
Transgene Detail

Summary

• Symbol: Tg(Tff2-EGFP,-cre)3aTcw
• Name: transgene insertion 3a, Timothy C Wang
• MGI ID: MGI:7520492
• Synonyms: TFF2-BAC-EGFP-Cre, Tff2-Cre
• Transgene: Tg(Tff2-EGFP,-cre)3aTcw Location: unknown
• Alliance: Tg(Tff2-EGFP,-cre)3aTcw page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Tff2-EGFP,-cre)3aTcw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tff2 (MGI:1306805)

• Mutation details: Using recombineering methods, the transgene consists of the EGFP-Cre-pA-FrtNeoFrt cassette with 60 bp homology arms upstream and downstream of the TFF2 translational stop codon in exon 4. Three founder lines, all of which displayed a similar pattern of expression throughout various organs (stomach, pancreas, and spleen) were generated. One line 3a was used for all experiments. (J:236280)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tff2 (mouse) Summary of all recombinase alleles driven by Tff2. Comparative matrix view of recombinase activities Alliance mouse Tff2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:236280 Dubeykovskaya Z, et al., Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nat Commun. 2016 Feb 04;7:10517
• All: 3 reference(s)