Alx3^{em1(cre/ERT2)Lanyu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Alx3^{em1(cre/ERT2)Lanyu}
• Name: aristaless-like homeobox 3; endonuclease-mediated mutation 1, Yu Lan
• MGI ID: MGI:7520584
• Synonyms: Alx3^CreERT2
• Gene: Alx3 Location: Chr3:107502347-107513092 bp, + strand Genetic Position: Chr3, 46.83 cM
• Alliance: Alx3^{em1(cre/ERT2)Lanyu} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Alx3^{em1(cre/ERT2)Lanyu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Alx3 (MGI:1277097)

• CRISPR/CAS-9 mediated gene targeting inserted the P2A-CreERT2 cassette into the exon 2 of the Alx3. (J:338957)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Alx3 (mouse) Summary of all recombinase alleles driven by Alx3. Comparative matrix view of recombinase activities Alliance mouse Alx3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alx3 Mutation: 14 strains or lines available

References

• Original: J:338957 Iyyanar PPR, et al., Developmental origin of the mammalian premaxilla. Dev Biol. 2023 Jul 29;503:1-9
• All: 1 reference(s)