Il17b^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il17b^em1Cya
• Name: interleukin 17B; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7522234
• Gene: Il17b Location: Chr18:61821006-61825609 bp, + strand Genetic Position: Chr18, 34.67 cM, cytoband D3
• Alliance: Il17b^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 2. (J:339366)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17b Mutation: 23 strains or lines available

References

• Original: J:339366 Zhang X, et al., Interleukin 17 B regulates colonic myeloid cell infiltration in a mouse model of DSS-induced colitis. Front Immunol. 2023;14:1055256
• All: 2 reference(s)