Lrtm2tm1b(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Lrtm2tm1b(EUCOMM)Wtsi |
Name: |
leucine-rich repeats and transmembrane domains 2; targeted mutation 1b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:7522451 |
Gene: |
Lrtm2 Location: Chr6:119292094-119307727 bp, - strand Genetic Position: Chr6, 56.73 cM
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Alliance: |
Lrtm2tm1b(EUCOMM)Wtsi page
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IMPC: |
Lrtm2 gene page |
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Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The L1L2_Bact_P cassette was inserted at position 119300389 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 119301846. The critical exon(s) is/are thus flanked by loxP sites. Cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:104881)
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Original: |
J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013; |
All: |
2 reference(s) |
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