Ttr^{tm1.1(cre)Card}
Targeted Allele Detail

Summary

• Symbol: Ttr^{tm1.1(cre)Card}
• Name: transthyretin; targeted mutation 1.1, Center for Animal Resources and Development
• MGI ID: MGI:7523194
• Synonyms: Ttr^{tm1.1(NLS/cre)Card}
• Gene: Ttr Location: Chr18:20798337-20807378 bp, + strand Genetic Position: Chr18, 11.47 cM
• Alliance: Ttr^{tm1.1(cre)Card} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Ttr^{tm1.1(cre)Card} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ttr (MGI:98865)

• The targeting construct replaced the coding sequence with a NLS-Cre. (J:104881)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ttr (mouse) Summary of all recombinase alleles driven by Ttr. Alliance mouse Ttr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttr Mutation: 46 strains or lines available

Notes

6NK-7 ES cells derived from C57BL/6N

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)