Stra8^em1(cre)Stpg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stra8^em1(cre)Stpg
• Name: stimulated by retinoic acid gene 8; endonuclease-mediated mutation 1, Stephanie A Pangas
• MGI ID: MGI:7523862
• Synonyms: Stra8^P2Acre
• Gene: Stra8 Location: Chr6:34897098-34916279 bp, + strand Genetic Position: Chr6, 15.2 cM
• Alliance: Stra8^em1(cre)Stpg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Stra8^em1(cre)Stpg expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Stra8 (MGI:107917)

• Mutation details: A P2A-Cre was inserted after the exon 10 of the Stra8 gene using CRISPR/Cas9-mediated genome editing in mouse pronuclear stage zygotes. (J:339445)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Stra8 (mouse) Summary of all recombinase alleles driven by Stra8. Alliance mouse Stra8 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stra8 Mutation: 35 strains or lines available

References

• Original: J:339445 Ahmed AA, et al., Generation of a novel Stra8-driven Cre recombinase strain for use in pre-meiotic germ cells in mice. Biol Reprod. 2023 Aug 10;109(2):184-191
• All: 1 reference(s)