Brix1^{tm1b(KOMP)Mbp}
Targeted Allele Detail

Summary

• Symbol: Brix1^{tm1b(KOMP)Mbp}
• Name: BRX1, biogenesis of ribosomes; targeted mutation 1b, Mouse Biology Program, UC Davis
• MGI ID: MGI:7524674
• Gene: Brix1 Location: Chr15:10474865-10486023 bp, - strand Genetic Position: Chr15, 5.35 cM
• Alliance: Brix1^{tm1b(KOMP)Mbp} page
• IMPC: Brix1 gene page

Mutation origin

• Mutant Cell Line: DEPD0006_11_C01
• Germline Transmission: Earliest citation of germline transmission: J:157064
• Parent Cell Line: JM8A1.N3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Brix1^{tm1a(KOMP)Mbp} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:157064)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brix1 Mutation: 28 strains or lines available

References

• Original: J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010
• All: 2 reference(s)