Plxnc1^{tm1(IL2RA)Mkil}
Targeted Allele Detail

Summary

• Symbol: Plxnc1^{tm1(IL2RA)Mkil}
• Name: plexin C1; targeted mutation 1, Mitsubishi Kagaku Institute of Life Sciences
• MGI ID: MGI:7526353
• Gene: Plxnc1 Location: Chr10:94626728-94780697 bp, - strand Genetic Position: Chr10, 49.09 cM, cytoband C3
• Alliance: Plxnc1^{tm1(IL2RA)Mkil} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104881
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Recombinase)
• Mutations: Insertion, Intragenic deletion
• Plxnc1^{tm1(IL2RA)Mkil} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL2RA (3559)

  Il2ra

  (MGI:96549)

• Plxnc1^{tm1(IL2RA)Mkil} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Plxnc1 (MGI:1890127)

• Mutation details: The targeting construct contains human IL2 receptor cDNA, Jellyfish GFP cDNA, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), human ALPP cDNA, rabbit beta globin poly A, herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, and mouse PlexinC1 genomic DNA. (J:104881)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Plxnc1 (mouse) Summary of all recombinase alleles driven by Plxnc1. Alliance mouse Plxnc1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnc1 Mutation: 80 strains or lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)