Nr1d1^em1Bwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nr1d1^em1Bwu
• Name: nuclear receptor subfamily 1, group D, member 1; endonuclease-mediated mutation 1, Baojian Wu
• MGI ID: MGI:7526547
• Synonyms: Rev-erbalpha^-
• Gene: Nr1d1 Location: Chr11:98658758-98666159 bp, - strand Genetic Position: Chr11, 62.66 cM
• Alliance: Nr1d1^em1Bwu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of 5 exons of the gene. (J:267593)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr1d1 Mutation: 40 strains or lines available

References

• Original: J:267593 Wang S, et al., REV-ERBalpha integrates colon clock with experimental colitis through regulation of NF-kappaB/NLRP3 axis. Nat Commun. 2018 Oct 12;9(1):4246
• All: 7 reference(s)