Tsnaxip1^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tsnaxip1^em1Osb
• Name: translin-associated factor X (Tsnax) interacting protein 1; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7531504
• Gene: Tsnaxip1 Location: Chr8:106554363-106571312 bp, + strand Genetic Position: Chr8, 53.04 cM, cytoband D2
• Alliance: Tsnaxip1^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 5717 bp deletion. Western blot analysis confirmed absence of protein in testis and spermatozoa. (J:340908)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tsnaxip1 Mutation: 31 strains or lines available

References

• Original: J:340908 Kaneda Y, et al., Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Andrology. 2023 Jul;11(5):799-807
• All: 1 reference(s)