Nmur1^{em1(icre)Hexu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nmur1^{em1(icre)Hexu}
• Name: neuromedin U receptor 1; endonuclease-mediated mutation 1, Heping Xu
• MGI ID: MGI:7531755
• Synonyms: Nmur1^iCre-TdT
• Gene: Nmur1 Location: Chr1:86313964-86317083 bp, - strand Genetic Position: Chr1, 43.94 cM, cytoband C5
• Alliance: Nmur1^{em1(icre)Hexu} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Nmur1^{em1(icre)Hexu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nmur1 (MGI:1341898)

• Mutation details: A sequence of Cre recombinase flanked by P2A coding sequences and followed by tdTomato-coding sequences (P2A-iCre-P2AtdTomato cassette) was inserted after the last coding exon of the endogenous Nmur1 gene. (J:340951)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nmur1 (mouse) Summary of all recombinase alleles driven by Nmur1. Comparative matrix view of recombinase activities Alliance mouse Nmur1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmur1 Mutation: 22 strains or lines available

References

• Original: J:340951 Li Y, et al., Neuromedin U programs eosinophils to promote mucosal immunity of the small intestine. Science. 2023 Sep 15;381(6663):1189-1196
• All: 1 reference(s)