Zswim8^em1Jtm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zswim8^em1Jtm
• Name: zinc finger SWIM-type containing 8; endonuclease-mediated mutation 1, Joshua T Mendell
• MGI ID: MGI:7537043
• Gene: Zswim8 Location: Chr14:20757620-20773687 bp, + strand Genetic Position: Chr14, 11.53 cM, cytoband B
• Alliance: Zswim8^em1Jtm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using dual single-guide RNAs created a deletion spanning exons 2 through 7. (J:338912)

Expression

In Mice Carrying this Mutation:	64 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zswim8 Mutation: 53 strains or lines available

References

• Original: J:338912 Jones BT, et al., Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes Dev. 2023 Aug 8
• All: 1 reference(s)