Taok1^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Taok1^em1Bcgen
• Name: TAO kinase 1; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7539359
• Gene: Taok1 Location: Chr11:77419988-77498641 bp, - strand Genetic Position: Chr11, 46.64 cM, cytoband B5
• Alliance: Taok1^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 3-8. (J:341142)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taok1 Mutation: 45 strains or lines available

References

• Original: J:341142 Wang J, et al., Taok1 haploinsufficiency leads to autistic-like behaviors in mice via the dorsal raphe nucleus. Cell Rep. 2023 Aug 31;42(9):113078
• All: 1 reference(s)